Maternal education has significant influence on progression in multiple sclerosis
نویسندگان
چکیده
ObjectiveThe identification of potential risk factors for disease severity is great importance in the treatment multiple sclerosis. The influence socioeconomic status on progression sclerosis (MS) sparsely investigated. Our aim was to investigate how adolescence influences later life.MethodsA total 1598 patients with from a well-defined population Norway were included. Detailed information progression, measured by expanded disability scale (EDSS) and score (MSSS), combined data factors. We used residency parental level education at patients’ age 16 exposure second-hand smoking as measure adolescence, adjusting same variables well use modifying treatments prevalence date 01.01.18.ResultsHigh maternal significantly associated less pronounced MSSS (β-coefficient -0.58, p = 0.015), younger lower EDSS onset, shorter time onset diagnosis. No significant associations found paternal MSSS. any before -0.49, p=0.004), while residence, current not.ConclusionThis study population-based, real-world cohort shows that has impact timely diagnosis MS. In addition treatment, also had an life.
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Maternal effect in multiple sclerosis.
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ژورنال
عنوان ژورنال: Multiple sclerosis and related disorders
سال: 2021
ISSN: ['2211-0356', '2211-0348']
DOI: https://doi.org/10.1016/j.msard.2021.103052